THESIS RELATED TO DEXMEDETOMIDINE

Routine anesthetic technique was used using propofol, fentanyl, vecuronium, nitrous oxide-oxygen and halothane. All variations of dosages and duration of both sedative agents were included. No patient had any other side effects. Single-dose dexmedetomidine attenuates airway and circulatory reflexes during extubation. We hypothesized that dexmedetomidine might be a useful agent to attenuate the response to extubation as it provides sedation, hemodynamic stability and does not depress respiration.

None of the patients in either group had any of the other side effects like respiratory depression, laryngospasm, bronchospasm, undue sedation [ Table 4 ]. For a smooth extubation, there should be no straining, movement, coughing, breath holding or laryngospasm. Some features of this site may not work without it. We found that most patients in study group were drowsy but responding to verbal commands Ramsay Sedation Scale 3 after extubation when compared to control group, where most patients belonged to Ramsay Sedation Scale 2. One patient in group D and 3 patients in group L had vomiting.

An important component of postoperative management following cardiac surgery is the use of sedation to reduce the stress response, facilitate assisted ventilation, and provide anxiolysis.

Studies were excluded if participants received both dexmedetomidine and propofol concurrently as a primary sedative. The patients in Group D received Dexmedetomidine thesi of 0.

Anesthesia techniques were standardized. Anesthestic techniques were standardized. There was lack of sufficient data to perform meta-analysis on in-hospital mortality rates. Any event of bradycardia, hypotension, vomiting, respiratory depression, laryngospasm or bronchospasm were noted. Any event of bradycardia, hypotension, vomiting, respiratory depression, laryngospasm or bronchospasm were noted.

Results The patients in the two groups were comparable for age, weight and male: Emergence — agitation score of most of the patients was 3 in group D and 2 in group L. Masters thesis, Coimbatore Medical College, Coimbatore. Extubation quality score of majority of patients was 2 in group A and 3 in group B. Nil Conflict of Interest: Results have been presented in narrative form when findings could not be pooled using meta-analysis.

  PERSONA 4 GOLDEN NANAKO SUMMER HOMEWORK

A novel drug and device in anesthesia : with focus on breathing and upper airway physiology

Later at one, three, five, dexmeddetomidine and fifteen minutes after injection in group d and one minute after injection in group L prior to extubation. SpO 2 Variation, shows line diagram comparing SpO2 between the two groups at dsxmedetomidine timings. Semin Anesth Perioper Med Pain.

Table 1 Demographic profile of two groups. One patient in group D and 3 patients in group L had vomiting. In the present study, the hemodynamic parameters in the study group were significantly stable during extubation when compared to the placebo group.

Interventions were propofol compared to dexmedetomidine as continuous infusions for sedation after cardiac surgery.

Author information Copyright and License information Disclaimer.

Later at one, three, five, ten and fifteen minutes after injection in group d and one minute after injection in group L prior to extubation. Any rrlated of laryngospasm, bronchospasm, desaturation, respiratory depression, vomiting, hypotension, undue sedation was noted.

A total of four studies were included in the review. There was insufficient evidence to determine significant differences in-hospital mortality rates. Heart rate, systolic, diastolic, mean arterial pressures were documented in both the groups during injection.

thesis related to dexmedetomidine

Later at one, three, five, ten and fifteen minutes after injection in group d and one minute after injection in group L prior to extubation.

  MILKHA SINGH ESSAY IN PUNJABI LANGUAGE

Interventions were propofol compared to dexmedetomidine as continuous infusions for sedation after cardiac surgery.

Randomized controlled trials RCTscontrolled trials, and prospective and retrospective cohort studies were considered for inclusion. Dexmedetomidine administered before tracheal extubation, was more effective in maintaining the hemodynamic stability, facilitated smooth tracheal extubation and had a better quality of recovery as compared to lignocaine.

Extubation of the trachea is associated with wide fluctuations in the hemodynamics and reflex relatev in airway reactivity leading to stress responses and airway irritation.

thesis related to dexmedetomidine

In our study, the incidence of bradycardia and hypotension was higher in study group than in control group. Extubation of the trachea is associated with wide fluctuations in the hemodynamics and reflex increases in airway reactivity leading to stress responses and airway irritation. Extubation of the trachea is associated with wide fluctuations in the hemodynamics and reflex increases in airway reactivity leading to stress responses and airway irritation. This study was undertaken to analyze the effects of dexmedetomidine versus lignocaine on the variations in hemodynamics and recovery responses during tracheal extubation.

Sedation protocols still need to be formulated.

Author: admin